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Pilot Tape Harvesting Study

Ensayo de BIOGEN INC. en Dermatitis atopica · Sano · Lupus eritematoso discoide · Lupus eritematoso cutaneo subagudo.

Más ensayos de: Dermatitis atópica.

Fase

no aplica

Estado

Completado

Participantes

37

previstos

Centros

2

Fin del objetivo primario

ago 2016

fecha real

Qué significa cada fase y cada estado.

Estudio observacional. Comenzó en may 2014.

Qué mide

Expresion de ARN de genes sospechosos de estar asociados con enfermedad de la piel en piel afectada frente a piel no afectada en participantes con enfermedad de la piel (dia 1)

Cómo lo describe el promotor

En el documentoEn inglés, del registroThe main objectives of the study are: To determine if RNA recovery from tape harvesting allows for the identification of a disease gene signature (e.g., interferon \[IFN\] signature for lupus) or other biomarkers that may differentiate affected from normal or unaffected skin; To determine if the lupus gene signature is differentially expressed in the epidermis from active discoid lupus erythematosus (DLE) or subacute cutaneous lupus erythematosus (SCLE) lesions when compared with unaffected skin from the same participants and from the skin of healthy volunteers (HVs); To determine if the atopic dermatitis (AD) gene signature is differentially expressed in the epidermis from active AD lesions when compared with unaffected skin from the same participants and from the skin of HVs; and To correlate the levels of transcripts of targeted genes in the skin by tape harvesting with those obtained from the blood.

Más ensayos de BIIB

Todos los de BIIB, en su ficha.

Ficha completa en ClinicalTrials.gov (NCT02125695), actualizada en sep 2016.